Chairman & Chief Cardiac Surgeon, Medanta – The Medicity
License VerifiedActive & In Good Standing
ID: DMC-11480
Delhi Medical Council (DMC) & Medical Council of India (MCI)
Professional Background & Bio
Dr. Naresh Trehan is a world-renowned cardiovascular and cardiothoracic surgeon, Founder, and Chairman of Medanta – The Medicity, Gurugram. With over 40 years of pioneering surgical experience, he has performed more than 48,000 successful open-heart surgeries and leads cardiovascular clinical literacy at mediguide4u.
“Myocardial Revascularization and Hemodynamic Stabilization in Off-Pump Coronary Artery Bypass Grafting (OPCAB)”
Institution: New York University Medical Center (NYU) & KGMU
Seminal surgical research on novel techniques for total arterial revascularization, beating-heart bypass mechanics, and organ preservation during high-risk cardiothoracic surgery without cardiopulmonary bypass.
Dr. Trehan reports zero commercial conflicts of interest or pharmaceutical sponsorships. Clinical reviews adhere strictly to ESC, AHA, and CSI practice guidelines.
Guides Medically Reviewed by Dr. Naresh Trehan, MBBS, MD, FACS
Verified for medical accuracy, safety guidelines, and clinical evidence.
Age-related muscle wasting (sarcopenia) and osteopenia are not inevitable consequences of aging. Discover evidence-based clinical protocols for progressive resistance training, dietary leucine-rich protein distribution, balance vestibular training, and home fall-risk reduction.
Benign prostatic hyperplasia (BPH) is the non-malignant adenomatous proliferation of the prostate transition zone, affecting over 70% of men over age 60. Review obstructive vs. irritative urinary symptoms, the International Prostate Symptom Score (IPSS), PSA evaluation, alpha-1 blockers, 5-alpha reductase inhibitors, and minimally invasive surgical therapies.
Obstructive Sleep Apnea (OSA) is a chronic sleep-related breathing disorder characterized by recurrent collapse of the upper airway, resulting in nocturnal oxygen desaturations, sympathetic surges, and sleep fragmentation. Review the STOP-Bang screening tool, Apnea-Hypopnea Index (AHI) severity tiers, CPAP compliance, and cardiovascular sequelae (hypertension, AFib, stroke).
High-sensitivity C-reactive protein (hs-CRP) is an acute-phase reactant synthesized by the liver in response to inflammatory cytokines (IL-6, TNF-alpha), serving as a powerful independent biomarker of vascular atherosclerosis and cardiovascular event risk. Understand clinical risk tiers (<1.0, 1.0–3.0, >3.0 mg/L), statin anti-inflammatory effects (JUPITER trial), and lifestyle interventions.
Headaches are among the most common neurological complaints, but treating a migraine as a tension headache frequently results in medication overuse and treatment failure. Review the pathophysiology of the trigeminovascular system, sensory auras, diagnostic criteria (ICHD-3), acute abortive treatments (triptans, gepants), and modern CGRP monoclonal antibodies.
Atherogenic dyslipidemia is a primary modifiable risk factor for atherosclerotic cardiovascular disease. Explore modern lipid science beyond basic total cholesterol—including Apolipoprotein B (ApoB), Non-HDL cholesterol, Lipoprotein(a), evidence-based statin dosing algorithms, and modern non-statin therapies (Ezetimibe, PCSK9 inhibitors).
Diabetic Peripheral Neuropathy (DPN) is the most common chronic microvascular complication of diabetes, affecting up to 50% of diabetic patients over their lifetime. Explore the biochemical mechanisms of neural glucotoxicity (polyol pathway sorbitol accumulation, microvascular vasa nervorum ischemia), clinical 10-g Semmes-Weinstein monofilament exams, and pharmacological pain management.
In exercise science and metabolic health, the debate between aerobic endurance training (cardio) and progressive resistance training (strength) is often framed as an either/or dichotomy. In physiological reality, these two modalities stimulate complementary cellular signaling pathways (AMPK vs. mTORC1) that synergize to maximize metabolic flexibility, body composition, cardiorespiratory fitness, and all-cause longevity.
Hypertension (BP ≥ 130/80 mmHg) is the single most modifiable risk factor for stroke, myocardial infarction and chronic kidney disease. Understand the physiological processes that result in lowering blood pressure without medication, including the DASH diet, salt/potassium balance, isometric training and autonomic modulation of stress.
Coronary Artery Disease (CAD) is the leading cause of mortality worldwide, resulting from atherosclerotic plaque accumulation within the epicardial coronary vessels. Explore modern diagnostic algorithms (Coronary Artery Calcium scoring, CT Coronary Angiography), medical management (high-intensity statins, beta-blockers, ACE inhibitors), and revascularization indications.
Peripheral artery disease (PAD) is caused by atherosclerotic narrowing in the lower extremity arteries, leading to exertional leg cramping (claudication), cold extremities, and slow-healing sores. Review diagnostic ABI thresholds, antiplatelet therapy, and supervised walking protocols.
Atrial Fibrillation (AFib) is the most common sustained cardiac arrhythmia, characterized by chaotic, disorganized electrical impulses firing in the atria at 300–600 bpm. Explore clinical stroke risk stratification using the CHA2DS2-VASc score, modern Direct Oral Anticoagulants (DOACs), rate vs. rhythm control strategies, and catheter pulmonary vein isolation.
Heart failure with preserved ejection fraction (HFpEF) occurs when the left ventricle becomes thick or stiff, preventing normal diastolic filling despite normal pumping capacity. Understand diagnostic markers like NT-proBNP, echocardiogram E/e' ratios, and evidence-based treatments including SGLT2 inhibitors and blood pressure control.
Cardiorespiratory fitness, quantified objectively as VO2 Max (maximal oxygen uptake in mL/kg/min), is the single most powerful modifiable biomarker predicting all-cause mortality and cardiovascular healthspan. Explore the cardiopulmonary Fick equation, the physiological boundaries of 5-tier Heart Rate Training Zones, mitochondrial Zone-2 base building, and the Norwegian 4x4 HIIT protocol.